Unusual case of locked trigger thumb due to tophaceous infiltration of the flexor tendon over the wrist: a lesson learned
- Keith Hay-Man Wan and
- Michael Siu-Hei Tse
- Orthopaedics and Traumatology, Kwong Wah Hospital, Hong Kong
- Correspondence to Dr Keith Hay-Man Wan; drkeithwan@gmail.com
Abstract
We report a rare case in which intratendinous gouty tophi were found within the flexor pollicis longus tendon at the wrist, causing locked thumb, which was misdiagnosed as trigger thumb.
Background
Trigger finger is a common condition frequently presented to the clinic. In severe cases, they may present as locked flexion contracture. Tophaceous gout over the wrist is a rare condition and it may mimic the presentation of severe trigger finger if a thorough physical examination is not performed.
Case presentation
A 46-year-old man with good previous health was presented to our clinic for inability to extend his right thumb. On physical examination, there was a tender nodule over the A1 pulley. There was a diffused swelling over the volar aspect of the forearm just proximal to the transverse carpal ligament. Due to prolonged inability to extend his thumb, he has developed a flexion contracture. Passive extension of the interphalangeal joint was possible on flexion of the metacarpophalangeal joint. Radiograph of the right thumb did not reveal any osteoarthritic change over the interphalangeal joint. The working diagnosis was locked trigger thumb and the patient was arranged for surgical release of the A1 pulley. Intraoperatively after releasing the A1 pulley, the fixed flexion contracture over the interphalangeal joint improved only slightly. After extending the incision proximally to the wrist, a mass of chalky substance was found infiltrating the flexor pollicis longus tendon just proximal to the transverse carpal ligament (figures 1 and 2). Debridement and excision of the chalky infiltration were performed.
A mass of chalky material proximal to the transverse carpal ligament upon dissection.

A mass of chalky material infiltrating the flexor pollicis longus tendon proximal to the transverse carpal ligament.

After extensive debulking of the mass, the flexor pollicis longus tendon was able to slide into the carpal tunnel (figure 3) and the interphalangeal joint (IPJ) was able to be passively extended fully. Histopathology evaluation confirmed the diagnosis of gouty tophi. Postoperatively the patient was able to fully extend his thumb.
Postdebridement of the chalky infiltration over the flexor pollicis longus tendon.

Patient was referred to the rheumatologists for assessment. Oral allopurinol was prescribed for the gouty arthritis.
Outcome and follow-up
On 1-year follow-up at our clinic, the range of motion of the thumb was full. There was no recurrence of the wrist swelling.
Discussion
Gout is a form of inflammatory arthritis caused by cellular deposition of monosodium urate crystal. Gouty tophi are chalky material as a result of accumulation of monosodium urate crystals that build up in the soft tissue of an articular joint.
We presented an unusual and rare case of gout in the flexor tendon of the wrist, which occurred in isolation in a patient with no previous history of the disease.
In our case, there was tophaceous gout over the wrist in which paratendinous gouty tophi were found within the flexor pollicis longus tendon, resulting in trigger thumb symptoms and flexion contracture over the interphalangeal joint. During the preoperative clinical assessment, we failed to recognise the correlation between the volar wrist swelling and the flexion contracture of the thumb interphalangeal joint. Due to the trigger thumb symptoms given by the patient and the clinical picture of interphalangeal joint flexion contracture, we treated the case as a severe trigger thumb with surgical release of the A1 pulley. Because of the absence of obvious osteoarthritic change over the interphalangeal joint, we assumed that the fixed flexion contracture was attributed by the stenosing tenosynovitis over the A1 pulley. On retrospect, we should have examined and investigated more carefully over the volar wrist swelling, like ultrasounography. Therimadasamy et al 1 reported ultrasonographic detection of the flexor tendons tophaceous infiltration as a heterogeneous mass.
Gouty tophi presenting as a mass over the wrist are uncommon, and the additional involvement of the flexor tendon resulting in the flexion contracture of the IPJ is even more rare. Kumar et al 2 have presented a similar case of gouty tophi over the volar aspect of the forearm, which was mistaken as tuberculosis tenosynovitis. Tajika et al 3 presented a case of locked trigger finger due to tophaceous infiltration of the wrist flexor tendon.
One must pay particular attention to the soft tissue while operating on patients with gouty arthritis on the hand and wrist region. The skin overlying a subcutaneous tophi should be gently handled in order not to impair the vascular supply.4 Sharp dissection should be used for most infiltrative lesions involving tendons and joint capsules.
Inevitably there exists a debate between radical surgery to avoid recurrence and the avoidance of tendon rupture. Most of the time, the tendon can be kept intact by shaving or curetting the tophaceous surface, followed by medical management resulting into subsequent slow resorption of the remaining tophus.5 However, in cases where there is advanced tophaceous infiltration of the tendon, surgical resection of the involved tendon followed by primary repair or subsequent tendon transfer can be considered.6
This is an uncommon and unusual case of tophaceous infiltration of the flexor pollicis longus tendon, resulting in locked thumb with fixed flexion at the interphalangeal joint. We should keep in mind the differential diagnosis of tophaceous gout in our clinical assessment with a more thorough physical examination and radiological investigation.
The diagnosis of trigger finger may look simple and straightforward at times, but it is of utmost importance to going over all the possible causes in our mind before operating on the patient.
Learning points
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In patients who presented with symptoms of trigger finger do not always assume that it is caused by stenosis over the A1 pulley.
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A thorough physical examination on the entire hand and wrist is of paramount importance in the order to make a correct diagnosis.
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If the diagnosis of severe trigger finger with flexion contracture over the interphalangeal joint is made, always try to test for the range of motion of the interphalangeal joint on flexing the metacarpophalangeal joint. If the passive flexion of the interphalangeal joint is improved, always consider whether the pathology lies more proximally over the wrist region.
Footnotes
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Contributors KW is the corresponding author of the manuscript. He was the attending surgeon of the case. He took major part in the preparation of this manuscript. MT is the co-author of this manuscript. He was the supervising surgeon of the case. He took part in the planning and supervisory work of this manuscript, as well as providing surgical support.
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Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
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Competing interests None declared.
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Patient consent for publication Obtained.
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Provenance and peer review Not commissioned; externally peer reviewed.
- © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
References
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